close
info
Search in:
Use the search below to find a dentist anywhere in the world!
Filter by category:
Filter by country:
Filter by type of treatment:
Keywords:
  • We Recommend We Recommend
    dental clinics, dental offices, dental hygienist
    We Recommend
     
    GO to Dental Clinic
  • Dental Services Dental Services
    find dental services and more
    Dental Services
     
    GO to Dental Service
  • Medical News Medical News
    read about dentistry, dental implants, cosmetic dentistry
    Medical News Dental Care for Your Baby
    Q. When should my child first see a dentist? A: Your child should visit a pediatric dentist between 24 and 30 months. Early examination and preventive care will protect...
     
    GO to Medical News
  • Medical Dictionary Medical Dictionary
    quick access to medical terms
    Medical Dictionary Saccade
    Abrupt rapid small movements of both eyes, such as when the eyes scan a line of print. The saccades can be divided into two distinct groups: the major saccades that are easily observed with the...
     
    GO to Dictionary
  • Dental Products Dental Products
    medical equipment, dental supplies, dental equipment
    Dental Products
     
    GO to Dental Product
  • Case Studies Case Studies
    case study examples, medical case studies, dental case study
    Case Studies What are dental bridges?
    When a tooth is missing, a three unit bridge can be a good choice for replacing it. In a three unit bridge an artificial tooth is connected on either side to crowns which are placed on the...
     
    GO to Case Studies
  • Dental Forum Dental Forum
    dentist forums, dental fear forum, dental phobia forum and more
    Dental Forum Gum Surgery
    Topics of discussion about Gum Surgery
     
    GO to Dental Forum
1/7
Join our newsletter!
 newsletter Join our newsletter! Subscribe arr
 
» T cell - A type of white blood cell that is of key[...]
» Table - One of the two layers of compact bone that make[...]
 


» Gingivitis Treatment - System
   Topics of discussion about Gingivitis Treatment

» Newcomer to the site - SimonJoseph
   Greeting to all, I am new here. My[...]

Scientists Profile Oral Mycobiome

Reset Decrease Increase
Scientists Profile Oral Mycobiome
Over the past few decades, researchers have come to recognize that the plaque-forming microbes in the oral cavity live as complex microbial communities. In addition to exploring the symbiotic interactions of oral bacteria, they also frequently note the presence of the other microbial inhabitants of the mouth, such as archaea and fungi. The problem is this recognition, particularly of the oral fungi, tends to be more conceptual than experiential. That’s because few oral fungi actually have been isolated and documented in the scientific literature, leaving many to believe that only a few species exist in the mouth.

As published online in January in the journal PLoS Pathogens, a team of National Institute of Dental and Craniofacial Research (NIDCR) grantees and their colleagues provide for the first time a comprehensive snapshot of the oral fungal mycobiome, or all of the fungal organisms—and their collective set of genes—that are present in the human mouth. Ghannoum, et al reported finding 74 culturable (can be grown in the laboratory) and 11 nonculturable fungal genera collectively in dental plaque samples from 20 healthy individuals. This breaks down to 101 distinct species, a clear indication that the oral mycobiome is not limited to a few species. Their article stated, “The oral mycobiome of at least 20% of the enrolled individuals included the 4 most common pathogenic fungi—Candida (present in 75% of the cohort), Aspergilla (35%), Fusarium (30%), and Cryptococcus (20%).” The researchers’ data also exhibited that 60 of the fungal genera identified in their profile are typically noninfectious and are ubiquitous in plants, soil, and air. As the scientists noted, previous attempts to catalogue the oral mycobiome ran into technical problems. Yet their published profile was made possible with a novel pyro­sequencing strategy that now opens up the mycobiome for further analysis.
The authors concluded, “The clinical relevance for the presence of a diverse population of fungal species in the oral cavity is unknown. It is possible that the presence of a given fungal isolate (eg, Candida, Aspergilla, Cryptococcus, and Fu­sarium) in an individual could be the first step in predisposing the host to opportunistic infections. In this regard, oral Candida colonization has been known to be a risk factor for Candida infections in immunocompromised patients.” They continued, “Understanding the relationships between different fungal species as well as between fungi and other members of the oral microbiome will shed light on the pathogenicity of these organisms and may lead to the discovery of novel therapeutic approaches for the prevention and treatment of oral complications.”




Source: www.dentistrytoday.com/

This article has been read by 1371 visitors.
Comments - Add your comment!
* - Required fields
Choose avatar: *    
Name *
Email * Will not be displayed
 
Comment *
2000 characters remaining
Security check
Enter the code below in the field next to it:
*This code help us prevent automated requests.

We welcome both positive and negative comments.
Do not include:
- Email addresses, phone numbers or other personal information that belong to you or to other people;
- Personal Ads;
- References to other comments or users who have posted comments;
- Obscene or offensive words.
Choose avatar: