Search in:
Use the search below to find a dentist anywhere in the world!
Filter by category:
Filter by country:
Filter by type of treatment:
  • We Recommend We Recommend
    dental clinics, dental offices, dental hygienist
    We Recommend
    GO to Dental Clinic
  • Dental Services Dental Services
    find dental services and more
    Dental Services
    GO to Dental Service
  • Medical News Medical News
    read about dentistry, dental implants, cosmetic dentistry
    Medical News SybronEndo
    SybronEndo The LA Axxess Diamond Bur, designed with Dr. Stephen Buchanan, is a high-speed diamond bur that makes effortless cutting of dentin and enamel possible. It...
    GO to Medical News
  • Medical Dictionary Medical Dictionary
    quick access to medical terms
    Medical Dictionary Xanthine
    A substance found in caffeine, theobromine, and theophylline and encountered in tea, coffee, and the colas. Chemically, xanthine is a purine.
    GO to Dictionary
  • Dental Products Dental Products
    medical equipment, dental supplies, dental equipment
    Dental Products
    GO to Dental Product
  • Case Studies Case Studies
    case study examples, medical case studies, dental case study
    Case Studies What is bone augmentation?
    When your jawbone has receded or lost its shape, the dentist can often augment it to replace missing bone and help new bone to grow. Depending where the bone loss has occurred, the dentist will...
    GO to Case Studies
  • Dental Forum Dental Forum
    dentist forums, dental fear forum, dental phobia forum and more
    Dental Forum Mouthwash
    Topics of discussion about different types of mouthwash.
    GO to Dental Forum
Join our newsletter!
 newsletter Join our newsletter! Subscribe arr
» Acid reflux - Acid reflux is a common condition and an abnormal[...]
» Vaccinia immune globulin - Vaccinia immune globulin is a blood product rich[...]

» Braces - System
   Topics of discussion about braces.

» Brackets - System
   Topics of discussion about Brackets

First vaccine for treating gum disease

Reset Decrease Increase
First vaccine for treating gum disease
First vaccine for treating gum disease
by Daniel Zimmermann, DTI

HONG KONG/LEIPZIG, Germany: Scientists from the University of Melbourne, Australia, have announced to have partnered with CSl Limited and Sanofi Pasteur, the countries largest biopharmaceutical companies, to further develop and commercialise a vaccine for the treatment of gum disease. The programme which took 10 years in development, involves bacterial peptides and proteins that trigger the immune response to periodontal inflammation. The vaccine is currently trialled in mouse models and expected to progress to clinical trials soon, the researchers said.

The new vaccine approach is targeting the ‘ring leader’ of a group of pathogenic bacteria called P. gingivalis that cause periodontitis. According to a US-based P. gingivalis research consortium, elevated levels of the organism were found in the majority of periodontal lesions, as well as in low levels in healthy sites. In addition, the organism also produces a number of enzymes that have been shown to interact with and degrade host proteins.

Although the bacterium can be eliminated through periodontal therapy, it is often found in recurrent infections.

“Periodontitis is a serious disease and dentists face a major challenge in treating it, because most people will not know they have the disease until it’s too late and the infection has progressed to advanced stages,” says Professor Eric Reynolds, CEO of the Cooperative Research Centre for Oral Health Science and the Head of The University of Melbourne’s Dental School. “This new approach will provide dentists and patients with a specific treatment.”

Traditional periodontal therapy involves manual scaling and cleaning, and even surgery with instruments or dental lasers in an effort to contain the bacterial infection. Reynold said their new line of vaccine products will possibly prevent the progression of the disease, rather than managing its symptoms and damaging consequences.

Sanofi Pasteur has an option to an exclusive world-wide license to commercialise the intellectual property associated with these products.


This article has been read by 1481 visitors.
Comments - Add your comment!
* - Required fields
Choose avatar: *    
Name *
Email * Will not be displayed
Comment *
2000 characters remaining
Security check
Enter the code below in the field next to it:
*This code help us prevent automated requests.

We welcome both positive and negative comments.
Do not include:
- Email addresses, phone numbers or other personal information that belong to you or to other people;
- Personal Ads;
- References to other comments or users who have posted comments;
- Obscene or offensive words.
Choose avatar: