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Medical Dictionary

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Hallervorden-Spatz disease

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means:
Hallervorden-Spatz disease A genetic disorder in which there is progressive neurologic degeneration with the accumulation of iron in the brain. The gene for the disease is on chromosome 20 in region 20p13-p12.3. The disease is characterized by progressive rigidity, first in the lower and later in the upper extremities. Involuntary movements of choreic or athetoid type may precede or accompany the rigidity. Both involuntary movements and rigidity may involve muscles supplied by cranial nerves, resulting in difficulties in articulation and swallowing. This disorder affects the muscular tone and voluntary movements progressively, making coordinated movements and chewing and swallowing almost impossible. Mental deterioration, emaciation, severe feeding difficulties, and visual impairment occur commonly in the late stages of the disease.
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"Hallervorden-Spatz disease" shown in the following materials:
Brain unable to localise tooth pain by Claudia Salwiczek, DTI ERLANGEN/LEIPZIG, Germany: The brain is not able to discriminate between a painful upper tooth and a painful lower tooth, researchers found. The[...]

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